Patent · US Active

Humanized anti-A β monoclonal antibody and application thereof

US12258386B2 · kind B2 · utility

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Assignee

Inventors

Key dates

Filing dateJan 17, 2020
Grant dateMar 25, 2025
Priority date
Expiry dateMar 12, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/4709
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are a humanized anti-Aβ monoclonal antibody and use thereof. The humanized anti-Aβ monoclonal antibody provided can inhibit the polymerization of Aβ monomers, protect nerve cells from the toxicity of Aβ, and have a certain effect on improving the cognitive learning and memory ability of Alzheimer's dementia model mice, and can be used for the treatment and diagnosis of diseases and disorders related to amyloidosis, such as Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.