Silicon-substituted rhodamine dyes and dye conjugates
US12258477B2 · kind B2 · utility
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Key dates
| Filing date | Aug 8, 2019 |
| Grant date | Mar 25, 2025 |
| Priority date | — |
| Expiry date | Jun 27, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6813
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Silicon-substituted rhodamine compounds are disclosed herein. Also described herein are SiR dyes comprising at least one vinyl group attached to the Si atom (10 position) of the SiR dye. Derivatives, functionalized versions, conjugates, kits, related synthetic methods and uses of SiR compounds also are provided. Silicon-rhodamine (SiR) dyes can provide bright fluorescence at far red wavelengths and exhibit good photostability. The compounds described herein can be useful for fluorescent labeling and detection of biological samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.