System and method for detecting small blood-tissue barrier disruption
US12262983B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 7, 2019 |
| Grant date | Apr 1, 2025 |
| Priority date | — |
| Expiry date | Oct 8, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/5601
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for detecting blood-tissue barrier breakdown or disruption is provided. The method includes acquiring first image data of a target region of a subject with a predetermined spatial resolution; administrating exogenous or endogenous tracer into the subject; acquiring second image data of the target region with the predetermined spatial resolution after administration of the tracer; differentiating healthy tissue and pathological tissue with blood-tissue barrier breakdown in the target region based on the first image data and the second image data; and visualizing or analyzing the blood-tissue barrier breakdown of pathological tissue based on the differentiation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.