Neratinib-cyclodextrin composition and method for preparing same
US12263226B1 · kind B1 · utility
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20Claims
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Key dates
| Filing date | Apr 23, 2024 |
| Grant date | Apr 1, 2025 |
| Priority date | — |
| Expiry date | Apr 23, 2044 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a composition comprising neratinib, or a pharmaceutically acceptable salt thereof, and hydroxypropyl-β-cyclodextrin, a method for preparing same, and use thereof. Study results show that the present invention can not only significantly improve the bioavailability of the active ingredient, but also eliminate food effects and adverse event diarrhea.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.