Patent · US Active

Antibody variable domains targeting the NKG2D receptor

US12264200B2 · kind B2 · utility

0Cited by
72References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 3, 2023
Grant dateApr 1, 2025
Priority date
Expiry dateNov 3, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/94
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antibody heavy chain variable domains that can be paired with antibody light chain variable domains to form an antigen-binding site targeting the NKG2D receptor on natural killer cells are described. Proteins comprising an NKG2D antigen-binding site, pharmaceutical compositions and therapeutic methods thereof, including for the treatment of cancer, are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.