Patent · US Active

Microorganism with knock-in at acetolactate decarboxylase gene locus

US12264348B2 · kind B2 · utility

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21Claims
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Key dates

Filing dateMay 2, 2023
Grant dateApr 1, 2025
Priority date
Expiry dateMay 2, 2043

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02E50/10
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Provided herein is a genetically engineered microorganism comprising knock-in of DNA at an acetolactate decarboxylase gene locus. Replacement of the acetolactate decarboxylase gene with DNA encoding one or more native or nonnative enzymes confers certain advantages, including fermentation stability and increased production of native and nonnative products from gaseous substrates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.