Patent · US Active

Cyclen based compounds, coordination compounds, peptides, pharmaceutical preparation, and use thereof

US12268757B2 · kind B2 · utility

0Cited by

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11Claims

0Family size

Assignee

USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. · CZ

Inventors

Miloslav Polasek · Praha, CZ
Jan Kretschmer · Nürnberg, DE

Key dates

Filing date	May 27, 2020
Grant date	Apr 8, 2025
Priority date	—
Expiry date	Jul 27, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K5/06191
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Cyclen based compounds of general formula (I) are disclosed. X is nitrogen and Y, Z are —CH—, or X, Z are —CH— and Y is nitrogen, or X, Y are —CH— and Z is nitrogen. R1 is independently selected from H; COOH; benzyloxycarbonyl; fluorenylmethyloxycarbonyl; tert-butoxycarbonyl; methylcarbonyl; trifluoromethylcarbonyl; benzyl; triphenylmethyl; tosyl; mesyl; benzyloxymethyl; phenylsulfonyl; ethoxycarbonyl; 2,2,2-trichloroethyloxycarbonyl; methoxycarbonyl; methoxymethyloxycarbonyl; R2 is selected from H; methylcarbonyl; tert-butyldimethylsilyl; (C1-C4)alkyl; R3 is independently selected from H; (C1-C6)alkyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.