Process for preparing a compound useful to treat mycoses

US12269814B2 · kind B2 · utility

Assignee

• PULMOCIDE LIMITED · GB

Inventors

• Thomas Christopher Colley · London, GB
• Kazuhiro Ito · London, GB
• Garth Rapeport · London, GB
• Peter Strong · London, GB
• Peter John Murray · London, GB
• Stuart Thomas Onions · Nottingham, GB
• Mihiro Sunose · Sawston, GB

Key dates

• Filing date: Apr 18, 2023
• Grant date: Apr 8, 2025
• Expiry date: Apr 18, 2043

Classification

• Technology area (CPC G): Physics
• CPC primary: G11C11/4074
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A combination therapy including one or more compounds of formula (I): wherein R represents hydrogen, halo, cyano, C1-4 haloalkyl, C1-4 haloalkoxy, or SO2NR5R6, R1a and R1b independently represent hydrogen or halo; R2 represents hydrogen, halo, cyano, C1-4 alkyl, C1-4 alkoxy, or C1-4 haloalkoxy; R3 represents halo, cyano, C1-4 alkyl, or C1-4 hydroxyalkyl; R4 represents hydrogen or C1-4 alkyl; X represents CH or N; Y represents N or CH which carbon atom may optionally be substituted by R, R1a or R1b; R5 and R6 independently represent hydrogen or C1-4 alkyl; or a pharmaceutically acceptable salt thereof; and a second or further active ingredient.