Chiral phosphoramidite auxiliaries and methods of their use
US12269839B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jan 9, 2023 |
| Grant date | Apr 8, 2025 |
| Priority date | — |
| Expiry date | Jan 9, 2043 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are P-stereogenic groups that may be used in the synthesis of compounds including stereochemically enriched P-stereogenic phosphorothioates. P-stereogenic groups may be provided in nucleoside phosphoramidites including a sugar bonded to a nucleobase and to a stereochemically enriched phosphoramidite as well as methods of their use and methods of making them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.