Anti-PD-L1/VEGF bifunctional antibody and use thereof
US12269885B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Mar 31, 2020 |
| Grant date | Apr 8, 2025 |
| Priority date | — |
| Expiry date | Oct 2, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an anti-PD-L1/VEGF bispecific antibody and a use thereof. Specifically, the present invention provides a bifunctional antibody, comprising: (a) anti-PD-L1 antibody or element; and (b) an anti-VEGF antibody or element linked to the anti-PD-L1 antibody or element. The bifunctional antibody of the present invention can simultaneously bind to VEGF and PD-L1, thereby exerting a therapeutic effect on VEGF and PD-L1-positive tumor cells (especially malignant tumor cells).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.