Antibodies which bind human fibrin or fibrinogen γC domain and methods of use
US12269894B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Mar 11, 2024 |
| Grant date | Apr 8, 2025 |
| Priority date | — |
| Expiry date | Mar 11, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are novel and improved antibodies that bind human fibrin or fibrinogen γC domain and methods of use thereof. In certain aspects, described herein are methods of inhibiting microglial activation. In certain aspects, described herein are pharmaceutical compositions comprising the antibodies that bind fibrin or fibrinogen γC domain. In certain aspects, the antibodies and methods described herein are used for treatment of degenerative neuronal disorders that involve inflammatory demyelination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.