Compositions and methods for treating cytokine release syndrome
US12274747B2 · kind B2 · utility
0Cited by
19References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2022 |
| Grant date | Apr 15, 2025 |
| Priority date | — |
| Expiry date | Jan 28, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for treating cancer and inhibiting cytokine release syndrome (CRS). The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a CD40 antagonist or a CAR-T cell expressing a CD40 antagonist in combination with a therapeutically effective amount of a CD3 multispecific antigen binding molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.