Patent · US Active

ROR-1 specific chimeric antigen receptors and uses thereof

US12275772B2 · kind B2 · utility

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58Claims
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Assignee

Inventors

Key dates

Filing dateJan 7, 2021
Grant dateApr 15, 2025
Priority date
Expiry dateFeb 5, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2510/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are chimeric antigen receptors (CARs) for cancer therapy, and more particularly, CARs containing a scFv from an anti-ROR-1 monoclonal antibody. Provided are immune effector cells containing such CARs, and methods of treating proliferative disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.