Functionalization of biopolymers with growth factor-binding peptides

US12275803B2 · kind B2 · utility

Assignee

• UNIVERSITEIT TWENTE · NL

Inventors

• João Francisco Ribeiro Pereira Simões Crispim · Eindhoven, NL
• Pascal Jonkheijm · Gronau, DE
• Daniël Bart Frederik Saris · Rochester, US

Key dates

• Filing date: Nov 30, 2017
• Grant date: Apr 15, 2025
• Expiry date: May 26, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K16/22
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure relates to a biopolymer that is functionalized with a peptide, preferably a growth factor-binding peptide. The disclosure further relates to a device comprising a functionalized biopolymer, to methods for treatment of a tissue pathology in a subject using a device according to the disclosure, to methods for coupling peptides to carbonyl groups of a biopolymer, and to a use of oxygen plasma for coupling a peptide to carbonyl groups of a biopolymer.