Chemical probe-dependent evaluation of protein activity and uses thereof
US12276654B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Nov 21, 2018 |
| Grant date | Apr 15, 2025 |
| Priority date | — |
| Expiry date | Mar 12, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2458/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed, in part, are methods and compositions for evaluating two or more target proteins from the same family through the use of a molecular construct that contains a targeting group and a retrieval tag. The method can, in some aspects, quantify the activity and function of the proteins of interest, visualize active enzymes at the subcellular and intercellular scale, and increase dynamic range via signal amplification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.