Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing
US12280057B2 · kind B2 · utility
0Cited by
4References
20Claims
0Family size
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Key dates
| Filing date | Sep 8, 2021 |
| Grant date | Apr 22, 2025 |
| Priority date | — |
| Expiry date | Feb 5, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to compositions and systems for improving tissue perfusion such that blood flow is increased, improving tissue healing time and reducing or eliminating tissue necrosis. In a preferred embodiment, the compositions comprise a phosphodiesterase inhibitor, a calcium channel blocker, a nitric oxide producer, and an α-adrenergic antagonist. Methods of making the compositions and using the compositions are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.