Patent · US Active

Method for sanitization of a chromatography column

US12280168B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignee

CYTIVA SWEDEN AB · SE

Inventors

Johan Avallin · Uppsala, SE
Anna Gronberg · Uppsala, SE
Anders Nilsson · Falköping, SE
Henrik Ingvarsson · Onsala, SE
Linda Persson · Uppsala, SE
Magnus Asplund · Uppsala, SE
Reinhard Braaz · Penzberg, DE

Key dates

Filing date	Mar 23, 2020
Grant date	Apr 22, 2025
Priority date	—
Expiry date	Mar 26, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K1/22
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

The invention discloses a method for sanitization of a bioprocess chromatography column, comprising the steps of: a) providing a bioprocess chromatography column with a packed bed of separation resin particles and a movable adapter, b) with the adapter in contact with the packed bed, conveying a sanitization fluid through the packed bed to a column outlet; c) raising the adapter to provide a gap between the packed bed and the adapter, d) lowering the adapter to close the gap; and e) conveying an equilibration liquid through the packed bed to a column outlet.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.