Process for synthesis of picolinamides

US12281076B2 · kind B2 · utility

Assignee

• CORTEVA AGRISCIENCE LLC · US

Inventors

• Nicholas R. Babij · Indianapolis, US
• Elizabeth O. McCusker · Carmel, US
• Gregory T. Whiteker · Carmel, US
• Neeraj Sane · Carmel, US
• Siyu Tu · Midland, US
• Xiaoyong Li · Midland, US
• Daniel W. Klosowski · Indianapolis, US
• Patrick T. McGough · Midland, US
• Meng Guo · Carmel, US
• Matthew Robinson · Indianapolis, US
• Jeffrey S. Nissen · Indianapolis, US
• Tyler Andrew DAVIS · Westfield, US
• Yan Hao · Zionsville, US

Key dates

• Filing date: Oct 15, 2020
• Grant date: Apr 22, 2025
• Expiry date: Jun 4, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present technology relates to processes, mixtures and intermediates useful for making picolinamide fungicides. The picolinamide compounds are prepared by processes that include coupling together a 4-methoxy-3-acyloxypicolinic acid with key 2-amino-L-alaninate esters derived from substituted 2-phenylethanols.