Patent · US Active

Isoindolinone substituted indoles and derivatives as RAS inhibitors

US12281099B2 · kind B2 · utility

0Cited by

0References

3Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Andreas Mantoulidis · Wien, AT
Andreas Gollner · Wien, AT
Dirk Kessler · Wien, AT
Laetitia Janine MARTIN · Wien, AT
Harald WEINSTABL · Wien, AT

Key dates

Filing date	Feb 25, 2020
Grant date	Apr 22, 2025
Priority date	—
Expiry date	Mar 3, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to new isoindolinone or isobenzofuranone substituted indoles and derivatives of formula (I) wherein the groups R1 to R7, R10 and n have the meanings given in the claims and specification, their use as inhibitors of RAS-family proteins and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.