Patent · US Active

Compounds useful for treating gastrointestinal tract disorders

US12281103B2 · kind B2 · utility

0Cited by
82References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 27, 2023
Grant dateApr 22, 2025
Priority date
Expiry dateDec 27, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.