Patent · US Active

Anti-pd-1 antibody-attenuated IL-2 immunoconjugates and uses thereof

US12281148B2 · kind B2 · utility

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3References
10Claims
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Assignee

Inventors

Key dates

Filing dateSep 3, 2024
Grant dateApr 22, 2025
Priority date
Expiry dateSep 3, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/75
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein-1 (hPD-1), and immunoconjugates comprising the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.