Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same
US12281180B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Jul 12, 2019 |
| Grant date | Apr 22, 2025 |
| Priority date | — |
| Expiry date | Jul 12, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are peptoid-peptide macrocycles. The peptoid-peptide macrocycles may have inhibitory activity towards the Wnt signaling pathway. The Wnt signaling pathway is associated with cancer and other diseases and conditions. Such diseases include, for example, pulmonary fibrosis. Also described are methods of making the peptoid-peptide macrocycles, compositions containing the peptoid-peptide macrocycles, and methods of using the peptoid-peptide macrocycles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.