Method and system for determining myocardial ischemia severity based on hemodynamic parameters estimation
US12285266B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2021 |
| Grant date | Apr 29, 2025 |
| Priority date | — |
| Expiry date | Oct 17, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H50/50
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
This disclosure relates generally to method and system for determining myocardial ischemia severity based on hemodynamic parameters estimation. Many patients suffer from myocardial ischemia due to narrowing of coronary artery resulting poor oxygen supply in cardiac muscles. The method includes receiving Electrophysiology (EP) signal from a simulated heart surface model to generate a single lead ECG template. The method further estimates hemodynamic parameters using a hemodynamic module based on the single lead ECG template and then estimates cardiac pressure-volume loop variables. The myocardial ischemia severity of the heart surface model is determined which includes one of moderate ischemia, severe ischemia and silent ischemia. Here, the cardiac source module is coupled with the hemodynamic module to determine cardiac transmembrane potential (TMP) of the heart surface model through contractility function. This method serves as a guidance platform for patient care such as synthetic data generation for disease classification pertaining to coronary artery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.