Sequence specific antimicrobials
US12285466B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | May 18, 2020 |
| Grant date | Apr 29, 2025 |
| Priority date | — |
| Expiry date | Dec 3, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/10371
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.