Patent · US Active

Self-antigen displaying nanoparticles targeting auto-reactive immune factors and uses thereof

US12285472B2 · kind B2 · utility

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2References
13Claims
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Key dates

Filing dateAug 20, 2015
Grant dateApr 29, 2025
Priority date
Expiry dateAug 20, 2035

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/6006
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides a composition, and method of use thereof, comprising self-antigen displaying nanoparticles to target auto-reactive immune components for treating and/or preventing the autoimmune diseases associated therewith. The nanoparticles can also be loaded with cytotoxic drugs for targeted cell killing or with immune-tolerizing compounds to normalize the immune regulation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.