Bone targeted antimicrobial oxazolidinone related compounds, formulations thereof, and uses thereof
US12285489B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Jun 25, 2019 |
| Grant date | Apr 29, 2025 |
| Priority date | — |
| Expiry date | Sep 27, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are bisphosphonate oxazolidinone compounds, and conjugates and pharmaceutical formulations thereof, that can include a bisphosphonate and an oxazolidinone (or an oxazolidinone antimicrobial or antibiotic agent, substituent or derivative thereof), where the oxazolidinone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate oxazolidinone compounds, conjugates and pharmaceutical formulations thereof. Also provided herein are methods of use of the compounds, conjugates and formulations for treating a bone disease or for use in preparing a formulation for the treatment a bone disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.