Anti-CD24 compositions and uses thereof

US12286485B2 · kind B2 · utility

Assignees

• OncoC4, Inc. · US
• Children's Research Institute, Children's National Medical Center · US

Inventors

• Yang Liu · Columbus, US
• Pan Zheng · Ann Arbor, US
• Rhonda Flores · Washington, US
• Hung-Yen Chou · McLean, US
• Zhihong Xue · Falls Church, US
• Peiying Ye · Potomac, US
• Martin Devenport · Gaithersburg, US

Key dates

• Filing date: May 13, 2019
• Grant date: Apr 29, 2025
• Expiry date: Aug 25, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are anti-CD24 antibodies that selectively bind human CD24 expressed in cancer cells, but not human CD24 expressed in non-cancerous cells, and the use of such antibodies in cancer therapy.