Engineered proline hydroxylase biocatalysts for hydroxylation of chemical compounds
US12286648B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Mar 8, 2023 |
| Grant date | Apr 29, 2025 |
| Priority date | — |
| Expiry date | Mar 11, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y114/11002
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.