Apparatus for applying thermal energy to a receptacle and detecting an emission signal from the receptacle
US12286669B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2020 |
| Grant date | Apr 29, 2025 |
| Priority date | — |
| Expiry date | Dec 17, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6484
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder that includes multiple receptacle wells. Each well can receive a receptacle and has a through-hole extending from an inner surface of the well to an outer surface of the holder. The apparatus includes multiple optical fibers, and each optical fiber has a first end in optical communication with an associated well and a second end in optical communication with an excitation signal source and/or an emission signal detector. The first end of each optical fiber is moveable with respect to the through-hole. A cover is movable between an open position and a closed position relative to the receptacle holder, and the first end of each optical fiber moves with respect to the through-hole of the associated well as the cover moves to the open or closed position or when the cover moves into or out of contact with any receptacles within the wells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.