Patent · US Active

Anti-matrix metalloproteinase 7 (MMP-7) inhibitory antibody and uses thereof

US12291578B2 · kind B2 · utility

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17Claims
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Inventors

Key dates

Filing dateFeb 10, 2020
Grant dateMay 6, 2025
Priority date
Expiry dateAug 7, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/52
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method of treating a disease associated with imbalanced or abnormal activity of MMP-7 is diclosed. The method comprises administration of an antibody comprising an antigen recognition region which binds a catalytic site of MMP-7, having complementarity determining region amino acid sequences as set forth in: SEQ ID NOs: 3, 4 and 5 (CDR3), sequentially arranged from N to C on a light chain of the antibody; and SEQ ID NOs: 6, 7 and 8, sequentially arranged from N to C on a heavy chain of the antibody.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.