Methods and/or use of oligonucleotide conjugates for assays and flow cytometry detections
US12291738B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 7, 2021 |
| Grant date | May 6, 2025 |
| Priority date | — |
| Expiry date | Jul 7, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2525/313
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.