Immediate release dosage form
US12296049B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 1, 2023 |
| Grant date | May 13, 2025 |
| Priority date | — |
| Expiry date | Sep 1, 2043 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An improved immediate release solid dosage form of naproxen with a certain particle size distribution for the intragranular portion, and a certain particle size distribution for the carbonate portion that allows naproxen to remain in solution and achieves fast dissolution and fast absorption of naproxen. The invention provides a naproxen dosage form that when administered to a human in a fasted state provides an average blood plasma naproxen concentration of at least 15-20 μg/ml in 10 minutes or less. The invention also provides a naproxen dosage form that when administered to a human in a fed state provides an average blood plasma naproxen concentration of at least 15-20 μg/ml in 50 minutes or less.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.