Regulated method for separating a mixture
US12296283B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2023 |
| Grant date | May 13, 2025 |
| Priority date | — |
| Expiry date | Nov 14, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC13K11/00
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention relates to a method for separating a mixture in a system comprising a plurality of chromatography columns, the method successively comprising, in a cyclical manner, in a given part of the system, steps of collecting a raffinate, injecting the mixture to be separated, collecting an extract and injecting a mobile phase; wherein the method further comprises measuring the purity and/or yield of a collected fraction, comprising: the determination, in a node of the system, of the histories of at least two variables that are representative of the concentration of at least two species contained in the mixture to be separated using at least one fast online detector; the determination of the concentration of at least two species of the mixture to be separated in the collected fraction based on these histories; and the determination of the purity and/or yield of the collected fraction based on these concentrations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.