Functionalization and purification of molecules by reversible group exchange
US12297221B2 · kind B2 · utility
0Cited by
11References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 1, 2023 |
| Grant date | May 13, 2025 |
| Priority date | — |
| Expiry date | Aug 1, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H1/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.