Transcriptomic index for characterizing the cellular repair response after soft tissue injury in diarthrodial joints
US12297500B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | May 9, 2018 |
| Grant date | May 13, 2025 |
| Priority date | — |
| Expiry date | Dec 20, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
One aspect of the invention provides methods for classifying the quality of a repair response after injury to a joint of a subject. In one embodiment, the method includes providing a tissue sample from the injured region of the joint and determining expression levels in the sample of a plurality of genes, including at least those genes listed in Table 1, Table 2 and Table 3. Another aspect of the invention provides methods of treating a human or veterinary subject having an injury to a joint based on the classification of the quality of the repair response.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.