Targeting ligands for tau pathology
US12298318B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 1, 2023 |
| Grant date | May 13, 2025 |
| Priority date | — |
| Expiry date | Feb 11, 2043 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and compositions for detecting tau pathology are described. The compositions for detecting tau pathology comprise a targeting ligand that specifically binds to a cell surface marker of tau pathology, wherein the targeting ligand is linked to a liposome that includes an imaging agent. The compositions can be used in a method for imaging tau pathology in a subject that comprises administering to the subject an effective amount of the composition to a subject and imaging at least a portion of the subject to determine if that portion of the subject exhibits tau pathology. The compositions can also be used to detect tau pathology in biological samples obtained from a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.