Patent · US Active

Methods and systems for slide imaging calibration

US12299917B2 · kind B2 · utility

0Cited by
0References
9Claims
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Assignee

Inventors

Key dates

Filing dateAug 12, 2024
Grant dateMay 13, 2025
Priority date
Expiry dateAug 12, 2044

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06T2207/10056
  • WIPO fieldOptics
  • WIPO sectorInstruments

Abstract

Various examples of systems and methods are provided for imaging calibration for slide processing. In one example, among others, a system for processing microscope slides includes a light source; an imaging device comprising a lens; and a slide positioner that can position the ground-glass portion of a slide between the light source and lens. Processing circuitry of the system can acquire an image of at least a section of the ground-glass portion at an initial position; analyze contrast of adjacent pixels with respect to a defined contrast characteristic; iteratively advance the lens and acquire additional images based upon analysis of contrast of adjacent pixels with respect to the defined contrast characteristic; and identify an optimal focal location of the lens based upon the defined contrast characteristic. Subsequent image acquisition via the lens can be based at least in part upon the optimal focal location.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.