Methods of treatment of temozolomide-resistant glioma using coenzyme Q10
US12303471B2 · kind B2 · utility
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126References
21Claims
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Key dates
| Filing date | Jan 10, 2022 |
| Grant date | May 20, 2025 |
| Priority date | — |
| Expiry date | Jan 10, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods and compositions for treatment of a subject with a glioma that has failed treatment with temozolomide (TMZ) comprising administration of a composition comprising a Coenzyme Q10 compound to the subject. The invention also provides a method of treating a cancer that exhibits increased Complex II activity in a subject comprising administration of a composition comprising a Coenzyme Q10 compound to the subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.