Patent · US Active

Microfluidic device for deformable beads enrichment and self-regulated ordering and encapsulation in droplets

US12303901B2 · kind B2 · utility

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20Claims
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Assignee

Inventors

Key dates

Filing dateJan 7, 2020
Grant dateMay 20, 2025
Priority date
Expiry dateJun 15, 2042

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L2400/086
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Disclosed herein are microfluidic devices comprising, one or more inlets in flow communication with one or more microfluidic channels, wherein the one or more inlets are adapted for receiving deformable beads, oil, and/or a suspension comprising buffer, cells, and/or particles, wherein the one or more microfluidic channels are in flow communication with the one or more inlets through a cross junction and define a fluid flow path therebetween, said fluid flow path forming a substantially planar substrate, and wherein the microfluidic channel is adapted to generate droplets. Also disclosed are methods of making and using the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.