Patent · US Active

Process for making an isoxazoline compound and intermediate thereof

US12304903B2 · kind B2 · utility

0Cited by
82References
28Claims
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Assignee

Inventors

Key dates

Filing dateDec 12, 2024
Grant dateMay 20, 2025
Priority date
Expiry dateDec 12, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure provides processes for making enantiomerically pure isoxazoline compounds of formula (1), The present disclosure also provides processes for making enantiomerically pure isoxazoline compounds of formula (1) characterized by improving the enantiomeric purity of 3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]thiophene-2-carboxylic acid by crystallization.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.