Fused bicyclic RAF inhibitors and methods for use thereof
US12304912B2 · kind B2 · utility
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3References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 16, 2023 |
| Grant date | May 20, 2025 |
| Priority date | — |
| Expiry date | Nov 16, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure generally relates to improved synthesis of fused bicyclic Raf inhibitors of formula (I), (I-A), (I-B), (II), or (III), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof. The disclosure also relates to method of using the compound of formula (I), (I-A), (I-B), (II), or (III), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, for treating diseases such as cancer, including colorectal cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.