Multivalent and bispecific antibody constructs and methods of use thereof
US12304954B2 · kind B2 · utility
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30Claims
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Key dates
| Filing date | Jun 18, 2024 |
| Grant date | May 20, 2025 |
| Priority date | — |
| Expiry date | Jun 18, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to multivalent, e.g., trivalent, and bispecific antibody constructs capable of binding an antigen on a cytotoxic effector cell and a tumor-associated antigen (TAA) on a tumor cell. Pharmaceutical compositions comprising such antibody constructs and methods of preparing and using such constructs and compositions, e.g., for the treatment of cancer, are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.