Microfluidic device and method of use for cell culture
US12305153B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | May 13, 2020 |
| Grant date | May 20, 2025 |
| Priority date | — |
| Expiry date | Apr 5, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A multi-layer microfluidic bioreactor is used in methods for culturing cells. A grooved semipermeable substrate can capture and grow cells using perfusion culture methods. Microfluidic geometry directs flow over grooves for cell expansion and along grooves for cell harvesting. The bioreactor and methods can be optimized for high density and automated processing for growth of cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.