Patent · US Active

Microfluidic device and method of use for cell culture

US12305153B2 · kind B2 · utility

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19Claims
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Key dates

Filing dateMay 13, 2020
Grant dateMay 20, 2025
Priority date
Expiry dateApr 5, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2740/16051
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A multi-layer microfluidic bioreactor is used in methods for culturing cells. A grooved semipermeable substrate can capture and grow cells using perfusion culture methods. Microfluidic geometry directs flow over grooves for cell expansion and along grooves for cell harvesting. The bioreactor and methods can be optimized for high density and automated processing for growth of cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.