Patent · US Active

HPPD variants and methods of use

US12305181B2 · kind B2 · utility

0Cited by

3References

13Claims

0Family size

Assignee

BASF Agricultural Solutions US LLC · US

Inventors

Fabien Poree · Frankfurt, DE
Bernd Laber · Idstein, DE
Gudrun Lange · Kelkheim, DE
Manuel Dubald · Raleigh, US
Roxanne Armstrong · Cary, US

Key dates

Filing date	Aug 12, 2019
Grant date	May 20, 2025
Priority date	—
Expiry date	Mar 17, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y113/11001
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

In the present invention, HPPD enzymes and plants containing them showing a full tolerance against several classes of HPPD-inhibitors are described.A set of HPPD enzymes have been designed which have either no or only a significantly reduced affinity to HPPD inhibitors and, at the same time, the rate of dissociation of the HPPD inhibitors of the enzyme is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors.In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.