Methods and systems for selection and treatment of patients with inflammatory diseases
US12305236B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Apr 26, 2019 |
| Grant date | May 20, 2025 |
| Priority date | — |
| Expiry date | Apr 3, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are methods and systems for identifying subjects suitable for treatment with an inhibitor of CD30L activity or expression, such as an anti-CD30L antibody. Methods and systems disclosed herein identify subjects suitable for treatment based on a presence of a genotype that is indicative of a disease or condition in the subject for which an inhibitor of CD30L is a suitable treatment. Exemplary conditions include both Crohns disease and primary sclerosing cholangitis. Compositions used to detect the genotypes described herein, and methods of using them are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.