Autonomous insemination in an intelligent automated in vitro fertilization and intracytoplasmic sperm injection platform
US12310625B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 2024 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Feb 2, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V2201/03
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for automated ICSI includes receiving at least one droplet containing an egg in a dish placed on a stage. The method includes using an artificial intelligence/machine learning system (AI/ML system) and an imaging system to detect a zona pellucida. The imaging system includes a microscopy system, a camera system, and a lighting system. The method includes holding the egg using a robotic microtool and lowering a robotic pipettor into the droplet. The method includes using the AI/ML system and imaging system to determine an area at which to hold the egg and positioning the robotic microtool to that area. The method includes using the AI/ML system and imaging system to instruct the robotic microtool to apply negative pressure to hold the egg to the robotic pipettor. The method includes using the AI/ML system and imaging system to determine a target location where zona ablation should be performed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.