Therapeutic uses for sodium thiosulfate formulations
US12311026B2 · kind B2 · utility
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21References
26Claims
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Key dates
| Filing date | Mar 15, 2024 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Mar 15, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01P2002/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum-based chemotherapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.