Nanotube-vesicle compositions and uses thereof

US12311053B2 · kind B2 · utility

Assignees

• Lawrence Livermore National Security, LLC · US
• The Regents of the University of California · US
• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Aleksandr Noy · Redwood City, US
• Nga Thuy HO · Oakland, US
• Gerhard HUMMER · Munich, DE
• Marc SIGGEL · Munich, DE

Key dates

• Filing date: Dec 14, 2020
• Grant date: May 27, 2025
• Expiry date: May 31, 2043

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B82Y5/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein is an engineered lipid-based vesicle optionally used for delivery of one or more payloads. The vesicle comprises a nanotube dimer or complex embedded with a lipid bilayer of the lipid-based vesicle. Also described herein are compositions, e.g., pharmaceutical compositions, and kits comprising the engineered lipid-based vesicle. In additional embodiments, further described herein are use of the engineered lipid-based vesicle for treating a disease or condition, for delivery to a target, or for labeling of a cell.