Long chain alkyl esteramine lipid compound, preparation method therefor and application thereof in nucleic acid delivery
US12312292B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Sep 27, 2023 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Sep 27, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a long chain alkyl esteramine lipid compound as shown in Formula I, preparation method therefor as well as use thereof in nucleic acid delivery, the long chain alkyl esteramine lipid compound provided by the present invention has an excellent encapsulation rate and delivery effect as a lipid molecule in delivering disease treatment or preventive agents, showing lower toxicity and certain tissue distribution characteristics, and providing a basis of more selections for delivering disease therapeutic or prophylactic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.