Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
US12312627B2 · kind B2 · utility
0Cited by
27References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 23, 2016 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Aug 16, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y208/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.